Prof. Thyagaraju Kedam, Biochemistry, Toxicology and Pharmacology

Prof. Thyagaraju Kedam, outlining his educational background, professional experience, research contributions, administrative roles, and memberships in scientific organizations. Academic and Professional Background of Prof. Thyagaraju Kedam Prof. Thyagaraju Kedam has an extensive academic and professional background, including significant roles in various educational institutions and research projects. He holds multiple degrees, including a PhD from Penn State University, and has served in various capacities at Sri Venkateswara University for over 40 years. • UGC Faculty Fellow and former Principal of University College of Pharmaceutical Sciences and College of Sciences at Sri Venkateswara University. Executive Council Member of Sri Venkateswara University • Studied PhD in Biochemistry in 1988 and a DSc in 2016 based on research and publications. • Held positions as Assistant Professor, Associate Professor, and Professor from 1982 to 2019, with a focus on Biochemistry. Research Contributions and PhD Supervision Prof. Kedam has produced 30 PhD graduates and has guided over 100 M Pharm students, contributing significantly to the field of Biochemistry. His research primarily focuses on glutathione S-transferases and their role in various biological processes. • Supervised 30 PhD candidates, with notable research on antioxidants, carcinogenesis, and lipid peroxidation. • Conducted extensive research on more than 12 GST proteins across various animal tissues. • Published findings on the expression of GSTs in rat brain tissues and their involvement in prostaglandin production. Administrative Roles and Contributions Prof. Kedam has held numerous administrative positions, contributing to the governance and development of academic programs at Sri Venkateswara University and beyond. His leadership roles have spanned various committees and councils. • Served as Head of Biochemistry multiple times and held positions on various boards and committees. • Acted as Director of Admissions and was involved in syllabus revisions at the state level. • Chaired and organized numerous academic conferences and workshops, enhancing the university's academic profile. Research Projects and Funding Prof. Kedam has been involved in multiple research projects funded by various national and international agencies, focusing on biochemical systems and their applications. His projects have received significant financial support, totaling over 9 crores. • Secured funding from UGC, CSIR, DST, and ICMR for various research initiatives. • Conducted projects on the characterization of antioxidants, genotoxicity studies, and the effects of carcinogens. • Received a DBT RRSFP Grant for over 9 crores from 2018 to 2021. Awards and Recognitions Prof. Kedam has received numerous awards and recognitions for his contributions to education and research, highlighting his impact in the field of Biochemistry. • Awarded the Indian Overseas Award in 1984 and the IFSI Siksha Rattan Purashkar in 2007. • Received the Indo-US Best Teacher Award in Pharmacy in 2013 and the AP State Teacher Award in 2017. • Recognized as a Fellow of several prestigious societies, including the Royal Society of Chemistry in 2023. Research Contributions in Biochemistry and Toxicology The text outlines a comprehensive list of research articles and contributions by K. Thyagaraju and collaborators in the fields of biochemistry, toxicology, and plant biochemistry. The publications span several decades and cover various topics, including the effects of toxins, antioxidant enzymes, and the biochemical properties of medicinal plants. • Numerous studies on glutathione S-transferases (GSTs) and their role in detoxification processes. • Research on the impact of dietary supplements, such as vitamin E, on health and disease. • Investigations into the effects of environmental toxins like acrylamide and cadmium on biological systems. • Contributions to understanding the biochemical mechanisms of medicinal plants, particularly in relation to oxidative stress and cancer. • Participation in various national and international conferences, showcasing ongoing research and findings. Publications and Their Impact The text lists a significant number of publications authored or co-authored by K. Thyagaraju, highlighting the breadth of research conducted over the years. These publications have contributed to advancements in understanding biochemical processes and the effects of various substances on health. • Over 100 research articles are published in reputable journals. • Topics include the characterization of enzymes, the effects of pollutants, and the biochemical analysis of medicinal plants. • Research findings have implications for health, nutrition, and environmental safety. • Several studies focus on the biochemical pathways involved in detoxification and oxidative stress responses. Conferences and Workshops Participation The text details K. Thyagaraju active participation in numerous conferences and workshops, reflecting his engagement with the scientific community and commitment to sharing knowledge. • Participation in over 80 national and international conferences. • Topics discussed include reproductive physiology, molecular biology, and environmental toxicology. • Contributions to workshops on biochemistry, biotechnology, and health sciences. • Engagement in discussions on the role of medicinal plants in health and disease. Books and Book Chapters Authored The text mentions several books and book chapters authored or edited by K. Thyagaraju, showcasing his contributions to academic literature in biochemistry and related fields. • Authored and edited multiple books on topics such as medicinal plants, drug delivery systems, and biochemistry. • Contributions include chapters on the biochemical roles of enzymes and the impact of environmental toxins. • Books serve as resources for students and researchers in the fields of biochemistry and pharmacology. Summary of Research Themes The text encapsulates the diverse research themes explored by K. Thyagaraju, emphasizing the significance of his work in advancing scientific knowledge. • Focus on the biochemical mechanisms of detoxification and the role of antioxidants. • Exploration of the effects of environmental pollutants on health and biological systems. • Investigation of the therapeutic potential of medicinal plants in combating oxidative stress and diseases. • Contributions to understanding the molecular basis of various biochemical processes and their implications for health. Academic Council Member of SVU and CUTN https://vidwan.inflibnet.ac.in/profile/591507

Cancer

Prof K Thyagaraju, the present Head of Biochemistry, is selected as member to the American Chemical society, for the year 2010 to 2011. Earlier its President has nominated him to ACS and at present he joined in that prestigious group. Dr Thyagaraju, a recipient of PhD from Pennsylvania State University, was serving the department since 1982 as Assistant, Associate (1995) and Professor (2003 onwards). In his academic career he published more than fifty papers in reputed journals and presented his work in more than 50 National and International conferences. He served as Principal Investigator on about nine projects funded by CSIR, DST, HRRD, UGC and ICMR. He has guided 18 PhD graduates in the department and at present under his guidance working more than 10 PhD graduates. His research work was mainly concerned on cancer biology markers and cell damage determination. The major achievement of his research is isolation of an immunomodulatory, a patentable, molecule from neem seed kernel. Further he is member and Honorary Secretary of Society of Biological Chemists of India and also member of Nutritional Society of India. Besides of all these he served as Director of Admissions, Liaison officer on welfare schemes of University, convenor of UCIC in Golden Jubilee celebrations, Chairman and member of various state and university committees, and at present serving as Academic Council member of Central University of Tamilnadu.

Hybanthus enneaspermus

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